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Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms
The homotypic cell adhesion molecule PECAM-1 is a major participant in the migration of leukocytes across endothelium. We examined the ability of a chimeric soluble sPECAM-1 fused to human IgG-Fc to impair leukocyte entry through the blood-brain barrier and reduce CNS autoimmunity. sPECAM-Fc impaire...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950937/ https://ncbi.nlm.nih.gov/pubmed/17467062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2007.03.014 |
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