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HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates
A cellular defense mechanism counteracts the deleterious effects of misfolded protein accumulation by eliciting a stress response. The cytoplasmic deacetylase HDAC6 (histone deacetylase 6) was previously shown to be a key element in this response by coordinating the clearance of protein aggregates t...
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Main Authors: | , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950856/ https://ncbi.nlm.nih.gov/pubmed/17785525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.436407 |
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