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HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

A cellular defense mechanism counteracts the deleterious effects of misfolded protein accumulation by eliciting a stress response. The cytoplasmic deacetylase HDAC6 (histone deacetylase 6) was previously shown to be a key element in this response by coordinating the clearance of protein aggregates t...

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Detalhes bibliográficos
Main Authors: Boyault, Cyril, Zhang, Yu, Fritah, Sabrina, Caron, Cécile, Gilquin, Benoit, Kwon, So Hee, Garrido, Carmen, Yao, Tso-Pang, Vourc’h, Claire, Matthias, Patrick, Khochbin, Saadi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950856/
https://ncbi.nlm.nih.gov/pubmed/17785525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.436407
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