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A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors

The neural crest (NC) is a highly motile cell population that gives rise to multiple tissue lineages during vertebrate embryogenesis. Here, we identify a novel effector of the small GTPase Rap, called RADIL, and show that it is required for cell adhesion and migration. Knockdown of radil in the zebr...

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Detalhes bibliográficos
Main Authors: Smolen, Gromoslaw A., Schott, Benjamin J., Stewart, Rodney A., Diederichs, Sven, Muir, Beth, Provencher, Heather L., Look, A. Thomas, Sgroi, Dennis C., Peterson, Randall T., Haber, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950852/
https://ncbi.nlm.nih.gov/pubmed/17704304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1561507
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