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Sp1 Expression Is Disrupted in Schizophrenia; A Possible Mechanism for the Abnormal Expression of Mitochondrial Complex I Genes, NDUFV1 and NDUFV2

BACKGROUND: The prevailing hypothesis regards schizophrenia as a polygenic disease, in which multiple genes combine with each other and with environmental stimuli to produce the variance of its clinical symptoms. We investigated whether the ubiquitous transcription factor Sp1 is abnormally expressed...

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Detalhes bibliográficos
Main Authors: Ben-Shachar, Dorit, Karry, Rachel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950689/
https://ncbi.nlm.nih.gov/pubmed/17786189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000817
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