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Effects of chronic opioid exposure on guinea pig mu opioid receptor in Chinese hamster ovary cells: Comparison with human and rat receptor

Chronic opioid treatment leads to agonist-specific effects at the mu opioid receptor. The molecular mechanisms resulting from chronic opioid exposure include desensitization, internalization and down-regulation of membrane-bound mu opioid receptors (MOP). The purpose of this study was to compare the...

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Bibliografiska uppgifter
Huvudupphovsmän: Wallisch, Michael, Nelson, Cole S., Mulvaney, Julia M., Hernandez, Heather S., Smith, Sue Ann, Olsen, George D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950480/
https://ncbi.nlm.nih.gov/pubmed/17343833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2007.02.001
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