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At clinically relevant concentrations the anaesthetic/amnesic thiopental but not the anticonvulsant phenobarbital interferes with hippocampal sharp wave-ripple complexes

BACKGROUND: Many sedative agents, including anesthetics, produce explicit memory impairment by largely unknown mechanisms. Sharp-wave ripple (SPW-R) complexes are network activity thought to represent the neuronal substrate for information transfer from the hippocampal to neocortical circuits, contr...

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Autori principali: Papatheodoropoulos, Costas, Sotiriou, Evangelos, Kotzadimitriou, Dimitrios, Drimala, Panagiota
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950312/
https://ncbi.nlm.nih.gov/pubmed/17672909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-60
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