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Evaluation of gene expression profiling in a mouse model of L-gulonolactone oxidase gene deficiency

Humans and guinea pigs are species which are unable to synthesize ascorbic acid (vitamin C) because, unlike rodents, they lack the enzyme L-gulonolactone oxidase (Gulo). Although the phenotype of lacking vitamin C in humans, named scurvy, has long been well known, information on the impact of lackin...

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Detalhes bibliográficos
Main Authors: Yan, Jian, Jiao, Yan, Li, Xinmin, Jiao, Feng, Beamer, Wesley G., Rosen, Cliff J., Gu, Weikuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950136/
https://ncbi.nlm.nih.gov/pubmed/18167513
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