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Aberration of FHIT gene is associated with increased tumor proliferation and decreased apoptosis-clinical evidence in lung and head and neck carcinomas.

BACKGROUND: Human FHIT (fragile histidine triad) gene is highly conserved gene homologous to a group of genes identified in prokaryotes and eukaryotes. Loss of FHIT function may be important in the development and/or progression of various types of cancer. MATERIALS AND METHODS: We undertook a clini...

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Autors principals: Pavelić, K., Krizanac, S., Cacev, T., Hadzija, M. P., Radosević, S., Crnić, I., Levanat, S., Kapitanović, S.
Format: Artigo
Idioma:Inglês
Publicat: 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950052/
https://ncbi.nlm.nih.gov/pubmed/11683369
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