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NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer
Background and aim: Colon cancer tumorigenesis is a multistep process of mutation accumulation in a number of oncogenes and tumour suppressor genes. NF1 gene protein, neurofibromin, acts as a tumour suppressor by turning the active form of Ras into an inactive form. This molecular switch has an impo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Copyright 2005 by Gut
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1774879/ https://ncbi.nlm.nih.gov/pubmed/15840687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.053348 |
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