Factors secreted by human neuroblastoma mediated doxorubicin resistance by activating STAT3 and inhibiting apoptosis.

BACKGROUND: The transcription factor Stat3 has been reported to play a key role in protecting cells against apoptosis by up-regulating expression of the anti-apoptotic gene BCl-xL. This investigation analyzes the relationship between the development of resistance to doxorubicin-mediated apoptosis in...

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Autori principali: Rebbaa, A., Chou, P. M., Mirkin, B. L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950050/
https://ncbi.nlm.nih.gov/pubmed/11474132
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