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Presence of DNA fragmentation and lack of neuroprotective effect in DFF45 knockout mice subjected to traumatic brain injury.

BACKGROUND: Apoptosis plays an important pathophysiologic role in neuronal cell loss and associated neurologic deficits following traumatic brain injury (TBI). DNA fragmentation represents one of the characteristic biochemical features of neuronal apoptosis and is observed after experimental TBI. DF...

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Detalhes bibliográficos
Main Authors: Yakovlev, A. G., Di, X., Movsesyan, V., Mullins, P. G., Wang, G., Boulares, H., Zhang, J., Xu, M., Faden, A. I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950023/
https://ncbi.nlm.nih.gov/pubmed/11471558
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