Human endotoxemia activates p38 MAP kinase and p42/44 MAP kinase, but not c-Jun N-terminal kinase.

BACKGROUND: All three major members of the MAPK family (i.e., p38 MAPK, p42/p44 MAPK, and c-Jun N terminal kinase (JNK)) have been shown to control cellular responses to inflammation in vitro. Therefore these kinases have been designated suitable targets for anti-inflammatory therapy. However, the e...

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Bibliographic Details
Main Authors: van den Blink, B., Branger, J., Weijer, S., Deventer, S. H., van der Poll, T., Peppelenbosch, M. P.
Format: Artigo
Language:Inglês
Published: 2001
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1950007/
https://ncbi.nlm.nih.gov/pubmed/11788789
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