p27Kip1 localizes to detergent-insoluble microdomains within lymphocyte membranes.

BACKGROUND: Low levels of the cyclin-dependent kinase inhibitor p27Kip1 are associated with poor prognosis in cancer. It is unclear whether this is related strictly to p27Kip1-mediated cell cycle inhibition or to other, possibly extranuclear, roles of this protein. In this study, we examined p27Kip1...

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Bibliografiske detaljer
Main Authors: Yaroslavskiy, B. B., Stolz, D. B., Watkins, S. C., Alber, S. M., Bradbury, N. A., Steinman, R. A.
Format: Artigo
Sprog:Inglês
Udgivet: 2001
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949993/
https://ncbi.nlm.nih.gov/pubmed/11474127
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