Insulin continues to induce plasminogen activator inhibitor 1 gene expression in insulin-resistant mice and adipocytes.

BACKGROUND: Although the association between insulin resistance and cardiovascular risk is well established, the underlying molecular mechanisms are poorly understood. The antifibrinolytic molecule plasminogen activator inhibitor 1 (PAI-1) is a cardiovascular risk factor that is consistently elevate...

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Autors principals: Samad, F., Pandey, M., Bell, P. A., Loskutoff, D. J.
Format: Artigo
Idioma:Inglês
Publicat: 2000
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949975/
https://ncbi.nlm.nih.gov/pubmed/11055587
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