Chlamydia trachomatis mouse pneumonitis lung infection in IL-18 and IL-12 knockout mice: IL-12 is dominant over IL-18 for protective immunity.

BACKGROUND: Interferon (IFN)-gamma is a key to protective immunity against a variety of intracellular bacterial infections, including Chlamydia trachomatis. Interleukin (IL)-18, a recently identified Th1 cytokine, together with IL-12 is a strong stimulator for IFN-gamma production. We investigated t...

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Main Authors: Lu, H., Yang, X., Takeda, K., Zhang, D., Fan, Y., Luo, M., Shen, C., Wang, S., Akira, S., Brunham, R. C.
Format: Artigo
Jezik:Inglês
Izdano: 2000
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949969/
https://ncbi.nlm.nih.gov/pubmed/10997341
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