Introduction of Culex Toxicity into Bacillus thuringiensis Cry4Ba by Protein Engineering

Bacillus thuringiensis mosquitocidal toxin Cry4Ba has no significant natural activity against Culex quinquefasciatus or Culex pipiens (50% lethal concentrations [LC(50)], >80,000 and >20,000 ng/ml, respectively). We introduced amino acid substitutions in three putative loops of domain II of Cr...

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Detalhes bibliográficos
Main Authors: Abdullah, Mohd Amir F., Alzate, Oscar, Mohammad, Marwan, McNall, Rebecca J., Adang, Michael J., Dean, Donald H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Invertebrate Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC194974/
https://ncbi.nlm.nih.gov/pubmed/12957922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.69.9.5343-5353.2003
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