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Fast Turnover of L1 Adhesions in Neuronal Growth Cones Involving Both Surface Diffusion and Exo/Endocytosis of L1 Molecules

We investigated the interplay between surface trafficking and binding dynamics of the immunoglobulin cell adhesion molecule L1 at neuronal growth cones. Primary neurons were transfected with L1 constructs bearing thrombin-cleavable green fluorescent protein (GFP), allowing visualization of newly exo...

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Autors principals: Dequidt, Caroline, Danglot, Lydia, Alberts, Philipp, Galli, Thierry, Choquet, Daniel, Thoumine, Olivier
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949362/
https://ncbi.nlm.nih.gov/pubmed/17538021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-12-1101
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