Protection of Hepatocytes from Cytotoxic T Cell Mediated Killing by Interferon-Alpha

BACKGROUND: Cellular immunity plays a key role in determining the outcome of hepatitis C virus (HCV) infection, although the majority of infections become persistent. The mechanisms behind persistence are still not clear; however, the primary site of infection, the liver, may be critical. We investi...

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Detalhes bibliográficos
Main Authors: Willberg, Christian B., Ward, Scott M., Clayton, Reginald F., Naoumov, Nikolai V., McCormick, Christopher, Proto, Sandra, Harris, Mark, Patel, Arvind H., Klenerman, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949144/
https://ncbi.nlm.nih.gov/pubmed/17726521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0000791
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