Disruption of the acyl-CoA:cholesterol acyltransferase gene in mice: Evidence suggesting multiple cholesterol esterification enzymes in mammals

The microsomal enzyme acyl-CoA:cholesterol acyltransferase (ACAT; EC 2.3.1.26) catalyzes the esterification of cellular cholesterol with fatty acids to form cholesterol esters. ACAT activity is found in many tissues, including macrophages, the adrenal glands, and the liver. In macrophages, ACAT is t...

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Main Authors: Meiner, Vardiella L., Cases, Sylvaine, Myers, Heather M., Sande, Eric R., Bellosta, Stefano, Schambelan, Morris, Pitas, Robert E., McGuire, James, Herz, Joachim, Farese, Robert V.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences of the USA 1996
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC19491/
https://ncbi.nlm.nih.gov/pubmed/8943057
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