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The C-terminal Extension of a Hybrid Immunoglobulin A/G Heavy Chain Is Responsible for Its Golgi-mediated Sorting to the Vacuole

We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells. Although plant cells can express large amounts of the antibody, a relevant proportion is normally lost to v...

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Udgivet i:Mol Biol Cell
Principais autores: Hadlington, Jane L., Santoro, Aniello, Nuttall, James, Denecke, Jürgen, Ma, Julian K-C., Vitale, Alessandro, Frigerio, Lorenzo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Cell Biology 2003
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC194906/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12808054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E02-11-0771
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