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Evaluation of the Oral Bioavailability of Low Molecular Weight Heparin Formulated With Glycyrrhetinic Acid as Permeation Enhancer

Low molecular weight heparin (LMWH) is the agent of choice for anticoagulant therapy and prophylaxis of thrombosis and coronary syndromes. However, its therapeutic use is limited due to poor oral bioavailability. The aim of this study was to investigate the oral delivery of LMWH, ardeparin formulate...

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Autori principali: Motlekar, Nusrat A., Srivenugopal, Kalkunte S., Wachtel, Mitchell S., Youan, Bi-Botti C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948842/
https://ncbi.nlm.nih.gov/pubmed/17710191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.20087
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