Akt/CREB/Cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate (TRAMP) model mediated by Nexrutine®, a Phellodendron amurense bark extract

PURPOSE: Development of prostate cancer (PCA) prevention strategies is an important priority to overcome high incidence, morbidity & mortality. Recently, we demonstrated that Nexrutine®, an herbal extract inhibits prostate cancer cell proliferation through modulation of Akt and CREB-mediated sig...

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Bibliographische Detailangaben
Hauptverfasser: Kumar, Addanki P, Bhaskaran, Shylesh, Ganapathy, Manonmani, Crosby, Katherine, Davis, Michael D, Kochunov, Peter, Schoolfield, John, Yeh, I-Tien, Troyer, Dean A, Ghosh, Rita
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948816/
https://ncbi.nlm.nih.gov/pubmed/17473212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-06-2974
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