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Drosophila Mcm10 Interacts with Members of the Prereplication Complex and Is Required for Proper Chromosome Condensation

Mcm10 is required for the initiation of DNA replication in Saccharomyces cerevisiae. We have cloned MCM10 from Drosophila melanogaster and show that it complements a ScMCM10 null mutant. Moreover, Mcm10 interacts with key members of the prereplication complex: Mcm2, Dup (Cdt1), and Orc2. Interaction...

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Detalles Bibliográficos
Main Authors: Christensen, Tim W., Tye, Bik K.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC194871/
https://ncbi.nlm.nih.gov/pubmed/12808023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E02-11-0706
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