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Fanconi anemia genes are highly expressed in primitive CD34(+ )hematopoietic cells

BACKGROUND: Fanconi anemia (FA) is a complex recessive genetic disease characterized by progressive bone marrow failure (BM) and a predisposition to cancer. We have previously shown using the Fancc mouse model that the progressive BM failure results from a hematopoietic stem cell defect suggesting t...

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Main Authors: Aubé, Michel, Lafrance, Matthieu, Brodeur, Isabelle, Delisle, Marie-Chantal, Carreau, Madeleine
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC194856/
https://ncbi.nlm.nih.gov/pubmed/12809565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2326-3-1
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