A functional interleukin 12 receptor complex is composed of two β-type cytokine receptor subunits

We have identified a cDNA from a human phytohemagglutinin-activated lymphoblast library encoding a protein that binds (125)I-labeled human interleukin 12 ((125)I-huIL-12) with a K(d) of about 5 nM when expressed in COS-7 cells. When coexpressed in COS-7 cells with the previously identified IL-12 β r...

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Bibliografische gegevens
Hoofdauteurs: Presky, David H., Yang, Hong, Minetti, Lisa J., Chua, Anne O., Nabavi, Nasrin, Wu, Chang-You, Gately, Maurice K., Gubler, Ueli
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1996
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19484/
https://ncbi.nlm.nih.gov/pubmed/8943050
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