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Inhibition of TGF-β signaling in normal lung epithelial cells confers resistance to ionizing radiation

PURPOSE: To address the functional role of radiation-induced TGF-β signaling in normal epithelial background, we selected spontaneously immortalized lung epithelial cell line derived from the normal lung tissue of dominant-negative mutant of TGF-β RII (ΔRII) transgenic mouse that expressed condition...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Reeves, Anna, Zagurovskaya, Marianna, Gupta, Seema, Shareef, Mohammed M., Mohiuddin, Mohammed, Ahmed, Mansoor M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1948025/
https://ncbi.nlm.nih.gov/pubmed/17448872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2006.12.057
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