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Relationship between the loss of neutralizing antibody binding and fusion activity of the F protein of human respiratory syncytial virus

To elucidate the relationship between resistance to HRSV neutralizing antibodies directed against the F protein and the fusion activity of the F protein, a recombinant approach was used to generate a panel of mutations in the major antigenic sites of the F protein. These mutant proteins were assayed...

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Detalhes bibliográficos
Main Authors: Liu, Changbao, Day, Nicole D, Branigan, Patrick J, Gutshall, Lester L, Sarisky, Robert T, Del Vecchio, Alfred M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1947961/
https://ncbi.nlm.nih.gov/pubmed/17623075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-71
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