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Screening for carriers of Tay-Sachs disease: a community project

Heterozygotes for Tay-Sachs disease can be distinguished by measuring the serum hexosaminidase activity and calculating the percentage of the heat-labile (A) form. We tested 7565 Ashkenazi Jews in Metropolitan Toronto and found a carrier frequency of 0.071. This figure was similar to the predicted f...

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Autors principals: Lowden, J. A., Zuker, S., Wilensky, A. J., Skomorowski, M. A.
Format: Artigo
Idioma:Inglês
Publicat: 1974
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1947670/
https://ncbi.nlm.nih.gov/pubmed/4854206
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