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The structural H19 gene is required for transgene imprinting

The product of the H19 gene is an untranslated RNA that is expressed exclusively from the maternal chromosome during mammalian development. The H19 gene and its 5′-flanking sequence are required for the genomic imprinting of two paternally expressed genes, Ins-2 (encodes insulin-2) and Igf-2 (encode...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Pfeifer, Karl, Leighton, Philip A., Tilghman, Shirley M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences of the USA 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC19455/
https://ncbi.nlm.nih.gov/pubmed/8943029
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