Peroxynitrite decomposition catalysts: Therapeutics for peroxynitrite-mediated pathology

Inflamed tissue is often characterized by the production of NO and superoxide. These radicals react at diffusion-limited rates to form the powerful oxidant peroxynitrite (PN). When protonated, PN decomposes into either nitrate or reactive intermediates capable of mediating tissue damage by oxidation...

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Autors principals: Salvemini, Daniela, Wang, Zhi-Qiang, Stern, Michael K., Currie, Mark G., Misko, Thomas P.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC19452/
https://ncbi.nlm.nih.gov/pubmed/9482943
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