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β-Arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression

Toll like receptors, the critical receptor family in innate immunity, have been shown to signal via both the ERK 1/2 and the transcription factor NFκB. β-Arrestins 1 and 2 have recently been implicated in modulation of NFκB signaling and ERK 1/2 activation. Using a number of approaches: mouse embryo...

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Detalhes bibliográficos
Main Authors: Fan, Hongkuan, Luttrell, Louis M., Tempel, George E., Senn, Joseph J., Halushka, Perry V., Cook, James A .
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1945129/
https://ncbi.nlm.nih.gov/pubmed/17418896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2007.02.009
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