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Depletion of Reduced Glutathione Enhances Motor Neuron Degeneration in vitro and in vivo

The mechanism of selective and age-dependent motor neuron degeneration in human amyotrophic lateral sclerosis (ALS) has not been defined and the role of glutathione (GSH) in association with motor neuron death remains largely unknown. A motor neuron-like cell culture system and a transgenic mouse mo...

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Detalhes bibliográficos
Main Authors: Chi, Liying, Ke, Yan, Luo, Chun, Gozal, David, Liu, Rugao
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1944995/
https://ncbi.nlm.nih.gov/pubmed/17150307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2006.09.064
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