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Heterozygous β‐globin gene mutations as a risk factor for iron accumulation and liver fibrosis in chronic hepatitis C

BACKGROUND: Iron accumulation is a well‐known risk factor for the progression of chronic hepatitis C (CHC) to fibrosis. However, the profibrogenic role of the genes controlling iron homeostasis is still controversial. AIM: To evaluate the relative role of haemachromatosis (HFE), ferroportin and β‐gl...

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Autors principals: Sartori, Massimo, Andorno, Silvano, Pagliarulo, Michela, Rigamonti, Cristina, Bozzola, Cristina, Pergolini, Patrizia, Rolla, Roberta, Suno, Anna, Boldorini, Renzo, Bellomo, Giorgio, Albano, Emanuele
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1942129/
https://ncbi.nlm.nih.gov/pubmed/17135308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2006.106641
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