Interferon-gamma is causatively involved in experimental inflammatory bowel disease in mice

Cytokines may be crucially involved in the pathogenesis of inflammatory bowel diseases (IBD), but it remains controversial whether interferon (IFN)-γ, a typical proinflammatory cytokine, is an essential mediator to cause the disorders. In the present study, IFN-γ(–/–) and wild-type (WT) C57BL/6 mice...

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Dettagli Bibliografici
Autori principali: Ito, R, Shin-Ya, M, Kishida, T, Urano, A, Takada, R, Sakagami, J, Imanishi, J, Kita, M, Ueda, Y, Iwakura, Y, Kataoka, K, Okanoue, T, Mazda, O
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
Soggetti:
Animal Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1942055/
https://ncbi.nlm.nih.gov/pubmed/17034586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03214.x
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