Hydroxychloroquine potentiates Fas-mediated apoptosis of rheumatoid synoviocytes

Inadequate apoptosis may contribute to the synovial hyperplasia associated with rheumatoid arthritis (RA). The Fas-associated death domain protein (FADD)-like interleukin (IL)-1β-converting enzyme (FLICE)-inhibitory protein (FLIP), which is an apoptotic inhibitor, has been implicated in the resistan...

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Hlavní autoři: Kim, W-U, Yoo, S-A, Min, S-Y, Park, S-H, Koh, H-S, Song, S-W, Cho, C-S
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2006
Témata:
Basic Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941983/
https://ncbi.nlm.nih.gov/pubmed/16734620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2006.03070.x
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