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Random linker-insertion mutagenesis to identify functional domains of herpes simplex virus type 1 glycoprotein B

Herpes simplex virus glycoprotein B (gB) is one of four glycoproteins essential for viral entry and cell fusion. Recently, an x-ray structure of the nearly full-length trimeric gB ectodomain was determined. Five structural domains and two linker regions were identified in what is probably a postfusi...

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Hlavní autoři: Lin, Erick, Spear, Patricia G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941792/
https://ncbi.nlm.nih.gov/pubmed/17666526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705926104
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