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Cost-utility analysis of genetic screening in families of patients with germline MUTYH mutations
BACKGROUND: MUTYH associated polyposis (MAP) is an autosomal recessive inherited disorder. Carriers of bi-allelic MUTYH germline mutations have a risk of approximately 60% to develop colorectal carcinoma (CRC). In the general population about 1.5% is a heterozygous MUTYH mutation carrier. Children o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1941726/ https://ncbi.nlm.nih.gov/pubmed/17605803 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-8-42 |
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