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Low-affinity Uptake of the Fluorescent Organic Cation 4-(4-(dimethylamino)styryl)-N-methylpyridinium iodide (4-Di-1-ASP) in BeWo Cells

Understanding the mechanisms of transport processes in the placenta can improve the safety and efficacy of drug delivery during pregnancy. Functional studies of Organic Cation Transporters (OCTs) are usually carried out using radioactivity, and a fluorescent marker would add flexibility to experimen...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Rytting, Erik, Bryan, Jordan, Southard, Marylee, Audus, Kenneth L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941684/
https://ncbi.nlm.nih.gov/pubmed/17174940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2006.11.020
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