Myeloperoxidase Interacts with Endothelial Cell-Surface Cytokeratin 1 and Modulates Bradykinin Production by the Plasma Kallikrein-Kinin System

During an inflammatory state, functional myeloperoxidase (MPO) is released into the vessel as a result of intravascular neutrophil degradation. One mechanism of resulting cellular injury involves endothelial internalization of MPO, which causes oxidative damage and impairs endothelial signaling. We...

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Main Authors: Astern, Joshua M., Pendergraft, William F., Falk, Ronald J., Jennette, J. Charles, Schmaier, Alvin H., Mahdi, Fakhri, Preston, Gloria A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Investigative Pathology 2007
Ábhair:
Regular Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1941610/
https://ncbi.nlm.nih.gov/pubmed/17591979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060831
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