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Effects of benzo(a)pyrene exposure on killifish (Fundulus heteroclitus) aromatase activities and mRNA

Cytochrome P450 aromatase (CYP19) plays an important role in steroid homoeostasis by converting androgens to estrogens. To evaluate the effects of benzo(a)pyrene (BaP), a model carcinogenic PAH and AhR ligand, on aromatase mRNA expression and enzyme activity, adult Fundulus were exposed to water-bor...

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Autori principali: Patel, Monali R., Scheffler, Brian E., Wang, Lu, Willett, Kristine L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1940838/
https://ncbi.nlm.nih.gov/pubmed/16458981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.aquatox.2005.12.009
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