Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: Implications for the mechanism of StAR action

Steroidogenic acute regulatory protein (StAR) plays a critical role in steroid hormone biosynthesis, presumably by facilitating the delivery of cholesterol to P450scc in the inner mitochondrial membranes. StAR is synthesized as a 37-kDa preprotein that is processed to a 30-kDa mature form by cleavag...

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Bibliografische gegevens
Hoofdauteurs: Arakane, Futoshi, Sugawara, Teruo, Nishino, Hideaki, Liu, Zhiming, Holt, John A., Pain, Debkumar, Stocco, Douglas M., Miller, Walter L., Strauss, Jerome F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences of the USA 1996
Onderwerpen:
Biological Sciences
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC19407/
https://ncbi.nlm.nih.gov/pubmed/8943003
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