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A constrained polynomial regression procedure for estimating the local False Discovery Rate

BACKGROUND: In the context of genomic association studies, for which a large number of statistical tests are performed simultaneously, the local False Discovery Rate (lFDR), which quantifies the evidence of a specific gene association with a clinical or biological variable of interest, is a relevant...

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Hlavní autoři: Dalmasso, Cyril, Bar-Hen, Avner, Broët, Philippe
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1940264/
https://ncbi.nlm.nih.gov/pubmed/17603882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-8-229
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