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Targeted Gene Disruption of the Cyclo (L-Phe, L-Pro) Biosynthetic Pathway in Streptomyces sp. US24 Strain

We have previously isolated a new actinomycete strain from Tunisian soil called Streptomyces sp. US24, and have shown that it produces two bioactive molecules including a Cyclo (L-Phe, L-Pro) diketopiperazine (DKP). To identify the structural genes responsible for the synthesis of this DKP derivativ...

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Détails bibliographiques
Auteurs principaux: Sioud, Samiha, Karray-Rebai, Ines, Aouissaoui, Hedi, Aigle, Bertrand, Bejar, Samir, Mellouli, Lotfi
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1940057/
https://ncbi.nlm.nih.gov/pubmed/17710112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2007/91409
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