The Ubiquitin-Conjugating Enzyme E2-EPF Is Overexpressed in Primary Breast Cancer and Modulates Sensitivity to Topoisomerase II Inhibition

We identified the ubiquitin-conjugating enzyme E2-EPF mRNA as differentially expressed in breast tumors relative to normal tissues and performed studies to elucidate its putative role in cancer. We demonstrated that overexpression of E2-EPF protein correlated with estrogen receptor (ER) negativity i...

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Main Authors: Tedesco, Donato, Zhang, Jianhuan, Trinh, Lan, Lalehzadeh, Guita, Meisner, Rene, Yamaguchi, Ken D, Ruderman, Daniel L, Dinter, Harald, Zajchowski, Deborah A
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939933/
https://ncbi.nlm.nih.gov/pubmed/17710163
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