Worse outcome and more chronic GVHD with peripheral blood progenitor cells than bone marrow in HLA-matched sibling donor transplants for young patients with severe acquired aplastic anemia

We analyzed the outcome of 692 patients with severe aplastic anemia (SAA) receiving transplants from HLA-matched siblings. A total of 134 grafts were peripheral blood progenitor cell (PBPC) grafts, and 558 were bone marrow (BM) grafts. Rates of hematopoietic recovery and grades 2 to 4 chronic graft-...

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Detalhes bibliográficos
Main Authors: Schrezenmeier, Hubert, Passweg, Jakob R., Marsh, Judith C. W., Bacigalupo, Andrea, Bredeson, Christopher N., Bullorsky, Eduardo, Camitta, Bruce M., Champlin, Richard E., Gale, Robert Peter, Fuhrer, Monika, Klein, John P., Locasciulli, Anna, Oneto, Rosi, Schattenberg, Antonius V. M. B., Socie, Gerard, Eapen, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1939910/
https://ncbi.nlm.nih.gov/pubmed/17475907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-081596
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