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Temperature-Sensitive Growth and Decreased Thermotolerance Associated with relA Mutations in Escherichia coli

The relA gene of Escherichia coli encodes guanosine 3′,5′-bispyrophosphate (ppGpp) synthetase I, a ribosome-associated enzyme that is activated during amino acid starvation. The stringent response is thought to be mediated by ppGpp. Mutations in relA are known to result in pleiotropic phenotypes. We...

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Detalhes bibliográficos
Main Authors: Yang, Xiaoming, Ishiguro, Edward E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193974/
https://ncbi.nlm.nih.gov/pubmed/13129947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.185.19.5765-5771.2003
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