Rrp47p Is an Exosome-Associated Protein Required for the 3′ Processing of Stable RNAs

Related exosome complexes of 3′→5′ exonucleases are present in the nucleus and the cytoplasm. Purification of exosome complexes from whole-cell lysates identified a Mg(2+)-labile factor present in substoichiometric amounts. This protein was identified as the nuclear protein Yhr081p, the homologue of...

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Autores principales: Mitchell, Philip, Petfalski, Elisabeth, Houalla, Rym, Podtelejnikov, Alexandre, Mann, Matthias, Tollervey, David
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2003
Materias:
Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC193929/
https://ncbi.nlm.nih.gov/pubmed/12972615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.19.6982-6992.2003
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