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Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements

Phylogenetic footprinting is an approach to finding functionally important sequences in the genome that relies on detecting their high degrees of conservation across different species. A new study shows how much it improves the prediction of gene-regulatory elements in the human genome.

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Detalhes bibliográficos
Main Authors: Zhang, Zhaolei, Gerstein, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC193683/
https://ncbi.nlm.nih.gov/pubmed/12814519
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