Impairment of alternative splice sites defining a novel gammaretroviral exon within gag modifies the oncogenic properties of Akv murine leukemia virus

BACKGROUND: Mutations of an alternative splice donor site located within the gag region has previously been shown to broaden the pathogenic potential of the T-lymphomagenic gammaretrovirus Moloney murine leukemia virus, while the equivalent mutations in the erythroleukemia inducing Friend murine leu...

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Main Authors: Sørensen, Annette Balle, Lund, Anders H, Kunder, Sandra, Quintanilla-Martinez, Leticia, Schmidt, Jörg, Wang, Bruce, Wabl, Matthias, Pedersen, Finn Skou
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2007
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1936429/
https://ncbi.nlm.nih.gov/pubmed/17617899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-46
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