Recombinant production of Streptococcus equisimilis streptokinase by Streptomyces lividans

BACKGROUND: Streptokinase (SK) is a potent plasminogen activator with widespread clinical use as a thrombolytic agent. It is naturally secreted by several strains of beta-haemolytic streptococci. The low yields obtained in SK production, lack of developed gene transfer methodology and the pathogenes...

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Hauptverfasser: Pimienta, Elsa, Ayala, Julio C, Rodríguez, Caridad, Ramos, Astrid, Van Mellaert, Lieve, Vallín, Carlos, Anné, Jozef
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2007
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1936427/
https://ncbi.nlm.nih.gov/pubmed/17610745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-6-20
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